Acinetobacter baumannii research group FOR 2251

List of Publications


Blaschke, U., Wilharm, G. (2017) Complete genome sequence of Acinetobacter sp. strain NCu2D-2 isolated from a mouse. Genome Announc 5:e01415-16.

Lytvynenko, I., Brill, S., Oswald, C., Pos, K. M.* (2016) Molecular basis of polyspecificity of the small multidrug resistance efflux pump AbeS from Acinetobacter baumannii.?J. Mol. Biol. 428: 644-657

Vargiu, A. V., Pos, K. M., Poole, K., Nikaido, H. (2016) Bad Bugs in the XXIst Century: Resistance Mediated by Multi-Drug Efflux Pumps in Gram-Negative Bacteria. Front Microbiol. 7: 833

Poppel, M.T., Skiebe, E., Laue, M., Bergmann, H., Ebersberger, I., Garn, T., Fruth, A., Baumgardt, S., Busse, H.J., Wilharm, G. (2016) Acinetobacter equi sp. nov. isolated from horse faeces. Int. J. Syst. Evol. Microbiol. 66: 881-888
Koenigs, A., Stahl, J., Averhoff, B., Göttig, S., Wichelhaus, T.A., Wallich, R., Zipfel, P.F., Kraiczy, P. (2016) CipA of Acinetobacter baumannii is a novel plasminogen and complement binding protein. J. Infect. Dis.213 : 1388-1399
Scholz, A., Stahl, J., de Berardinis, V., Müller, V., Averhoff, B. (2016) Osmotic stress response in Acinetobacter baylyi: Identification of a glycine-betaine biosynthesis pathway and regulation of osmoadaptive choline uptake and glycine betaine synthesis through a choline-responsive BetI repressor. Environ. Microbiol. Reports8 : 316-322


Weidensdorfer, M., Chae, J.I., Makobe, C., Stahl, J., Averhoff, B., Müller, V., Schürmann, C., Brandes, R., Wilharm, G., Ballhorn, W., Christ, S., Linke, D., Fischer, D., Göttig, S., Kempf, V. (2015) Analysis of endothelial adherence of Bartonella henselae and Acinetobacter baumannii using a dynamic human ex vivo infection model. Infect. Immun. 84 : 711-722
Stahl, J., Bergmann, H., Göttig, S., Ebersberger, I., Averhoff, B. (2015) Acinetobacter baumannii virulence is mediated by the concerted action of three phospholipases D. PLoS ONE 10: e0138360
Nemec, A., Krizova, L., Maixnerova, M., Sedo, O., Brisse, S., and Higgins, P. G. (2015) Acinetobacter seifertii sp. nov., a member of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex isolated from human clinical specimens. Int. J. Syst. Evol. Microbiol. 65 : 934-942
Averhoff, B. (2015) Acinetobacter baumannii - understanding and fighting a new emerging pathogen. Environ. Microbiol. 7 : 6-8
Waidmann, O., Kempf, V. A., Brandt, C., Zeuzem, S., Piiper, A., and Kronberger, B. (2015) Colonisation with multidrug-resistant bacteria is associated with increased mortality in patients with cirrhosis. Gut 64 : 1183-1184
Sand, M., Rodrigues, M., Gonzalez, J. M., de Crecy-Lagard, V., Santos, H., Müller, V., and Averhoff, B. (2015) Mannitol-1-phosphate dehydrogenases/phosphatases: a family of novel bifunctional enzymes for bacterial adaptation to osmotic stress. Environ. Microbiol. 17 : 711-719


Goettig, S., Gruber, T. M., Higgins, P. G., Wachsmuth, M., Seifert, H., and Kempf, V. A. (2014) Detection of pan drug-resistant Acinetobacter baumannii in Germany. J. Antimicrob. Chemother. 69 : 2578-2579
Sand, M., Stahl, J., Waclawska, I., Ziegler, C., and Averhoff, B. (2014) Identification of an osmo-dependent and an osmo-independent choline transporter in Acinetobacter baylyi: implications in osmostress protection and metabolic adaptation. Environ. Microbiol. 16 : 1490-1502
Zander, E., Bonnin, R. A., Seifert, H., and Higgins, P. G. (2014) Characterization of blaOXA-143 variants in Acinetobacter baumannii and Acinetobacter pittii. Antimicrob. Agents. Chemother. 58 : 2704-2708
Zander, E., Seifert, H., and Higgins, P. G. (2014) Insertion sequence IS18 mediates overexpression of blaOXA-257 in a carbapenem-resistant Acinetobacter bereziniae isolate. J. Antimicrob. Chemother. 69 : 270-271
Heindorf, M., Kadari, M., Heider, C., Skiebe, E., and Wilharm, G. (2014) Impact of Acinetobacter baumannii superoxide dismutase on motility, virulence, oxidative stress resistance and susceptibility to antibiotics. PLoS One 9, e101033
Kleinkauf, N., Hausemann, A., Kempf, V. A., Gottschalk, R., and Heudorf, U. (2014) Burden of carbapenem-resistant organisms in the Frankfurt/Main Metropolitan Area in Germany 2012/2013 - first results and experiences after the introduction of legally mandated reporting. BMC Infect. Dis. 14 : 446
Zander, E., Fernández-González, A., Schleicher, X., Dammhayn, C., Kamolvit, W., Seifert, H., and Higgins, P. G. (2014) Worldwide dissemination of acquired carbapenem-hydrolysing class D & beta-lactamases in Acinetobacter spp. other than Acinetobacter baumannii. Int. J. Antimicrob. Agents 43 : 375-377
Hischebeth, G.T., Wimmer, M.D., Molitor, E., Seifert, H., Gravius, S., Bekeredjian-Ding, I. (2014) Multidrug resistant Acinetobacter baumannii reaches a new frontier: prosthetic hip joint infection. Infection 43 : 95-97


Wilharm, G., Piesker, J., Laue, M., and Skiebe, E. (2013) DNA uptake by the nosocomial pathogen Acinetobacter baumannii occurs during movement along wet surfaces. J. Bacteriol. 195 : 4146-4153
Higgins, P. G., Perez-Llarena, F. J., Zander, E., Fernandez, A., Bou, G., and Seifert, H. (2013) OXA-235, a novel class D beta-lactamase involved in resistance to carbapenems in Acinetobacter baumannii. Antimicrob. Agents. Chemother. 57 : 2121-2126
Proschak, A., Lubuta, P., Gruen, P., Loehr, F., Wilharm, G., De Berardinis, V., and Bode, H. B. (2013) Structure and biosynthesis of fimsbactins A-F, siderophores from Acinetobacter baumannii and Acinetobacter baylyi. Chembiochem. 14 : 633-638
Schleicher, X., Higgins, P. G., Wisplinghoff, H., Koerber-Irrgang, B., Kresken, M., and Seifert, H. (2013) Molecular epidemiology of Acinetobacter baumannii and Acinetobacter nosocomialis in Germany over a 5-year period (2005-2009). Clin. Microbiol. Infect. 19 : 737-742
Sand, M., Mingote, I., A., Santos, H., Müller, V., and Averhoff, B. (2013) Mannitol, a compatible solute synthesized by Acinetobacter baylyi in a two-step pathway including a salt-induced and salt-dependent mannitol-1-phosphate dehydrogenase. Environ. Microbiol. 15 : 2187–2197
Zander, E., Chmielarczyk, A., Heczko, P., Seifert, H., and Higgins, P. G. (2013) Conversion of OXA-66 into OXA-82 in clinical Acinetobacter baumannii isolates and association with altered carbapenem susceptibility. J. Antimicrob. Chemother. 68 : 308-311
Zander, E., Higgins, P. G., Fernández-González, A., and Seifert, H. (2013) Detection of intrinsic blaOXA-51-like by multiplex PCR on its own is not reliable for the identification of Acinetobacter baumannii. Int. J. Med. Microbiol. 303 : 88-89
Choi, J.Y., Ko, G., Jheong, W., Huys, G., Seifert, H., Dijkshoorn, L., Ko, K.S. (2013) Acinetobacter kookii sp. nov., isolated from soil. Int. J. Syst. Evol. Microbiol. 63 : 4402–4406
Müller, V., Kempf, V.A.J. (2014) Acinetobacter baumannii – ein Pathogen mit zunehmender Bedeutung. Biospektrum 20 : 703